Aevaluation of earthquake resistance behavior of reinforced concrete moment-resisting structures structures having G+10 and G+20 structural arrangementswas carried out through STAAD Pro V8i software V8i software analytical software under various earthquake-prone zones defined according to IS 1893:2016 provisions. The study examined the influence of structural geometry and bay arrangement on horizontal displacement response, inter-storey drift, floor-wise shear force, and stiffness characteristics. Three structural configurations with varying bay distributions in the X and Z directions were analyzed under static and dynamic loading conditions. Load combinations were developed according to Indian Standard provisions considering dead load, live load, and earthquake-induced effects. The analytical results demonstrated that taller buildings experienced larger horizontal displacement responses and inter-storey drift due to increased flexibility and reduced lateral rigidity. The G+20 models exhibited nearly 30–40% greater displacement response compared to G+10 structures under identical earthquake-induced conditions. Structural models with balanced bay spacing showed improved stiffness distribution and lower drift concentration across intermediate floors. Maximum floor-wise shear force was observed at lower floor levels because of cumulative earthquake-induced force transfer toward the foundation level. The comparative evaluation confirmed that optimized bay configuration significantly enhances earthquake-induced stability by controlling displacement and improving lateral load resistance. The study provides practical guidance for The earthquake-relatedplanning and analysis of medium- and tall-rise reinforced concrete buildings in earthquake-prone regions.