Hair loss following chemotherapy and major surgery is often multifactorial, with profound physical and psychological impact. Conventional and supportive measures frequently provide limited relief. This case report documents the successful classical homeopathic management of severe diffuse hair loss in a 39-year-old female with a history of lung cancer, chemotherapy, surgery, hypothyroidism, and emotional distress. A holistic individualized approach based on totality of symptoms and constitutional prescribing resulted in sustained clinical improvement and psychological restoration. A marked transformation in physical, emotional, and quality-of-life parameters was achieved at Dr Batra’s® Homeopathy Clinic.