Microorganisms, like all cells, produce heat as a by product of the enzymatic catabolism of substrate and synthesis of cell material. In the world, first time the energy of microorganism is absorbed, released or transformed one into another mechanism equation was discovered by Shagj J (Rolex awards Jambalyn Shagj: Heat generation and accumulation in the mammalian and human large intestine). Assumig the heat was spread over a 70 kg person and there was no heat loss, gut bacteria would raise body temperature by about 1.0 °C/h.The colonic epithelium drives 60%-70% of its energy from bacterial fermentation products such as acetate, propionate, butyrate, lactate, pyruvate. This phenomenon is called bio-energetics feedback of host cell and bacteria.The large intestine’s lenght of approximate family of a mammifier is demonstrated that the adaptation potential in the thermo-situation. It depends on there are evolvement, chronologic factor, geographic condition and abruptness of weather.
