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Influence of exogenous estradiol on the lipids profile, ast, alt and alp of intact and castrated male rabbits

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Author: 
Tamour Elkhier, Shams-Eldein Hassaballa and ShadiaAbdo-Elatti Omer
Abstract: 

This study was conducted to investigate the changes on lipids profiles, AST, ALT and ALP enzymes of (intact and castrated) males rabbits due to exposure to estradiol benzoate via intramuscular injection routeeach alternative day for 30 days period. The result of this study shown that the injection of estradiol benzoate at doses of 40, 80 and 120 µgm/ rabbit intramuscularly were not induced any significant (P˃0.05) changes on lipids profile of intact and castrated male rabbits while HDL was significantly (P˂0.05) increased at a dose 40 μg in intact male rabbits. AST and ALP were significantly (P˂0.05) decreased in castrated male rabbits but not changed (P˃0.05) in intact male rabbits, while ALT was not changed (P˃0.05) in castrated and intact male rabbits expect at a dose of 120 µgm was shown significant (P˂0.05) increase in intact male rabbits.

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