The investigation was carried out with the purpose of determining the grade of incidence of the fluvial and terrestrial existent malacofauna in the municipality Santa Clara, in the human health and animal during the period corresponding to the years 2011 -2015. The species of mollusks were identified, so much fluvial and terrestrial existent in the municipality Santa Clara whose identification process, was made in the laboratory of the Provincial Unit of Surveillance and Antivectorial Fights. The obtained data were processed by means of the statistical package Microsoft Office Excel, version 2007 and with the package Statgraphics, to determine the graph of tendency curve. Being evidenced that the species well represented and distributed, as for the fluvial mollusks, they turned out to be: Tarebia granifera, Melanoides tuberculata, Corbicula fluminea and Physa acuta; while in the case of the terrestrial ones, they were: Pratycorella griseola and Subulina octana. A wide proliferation of the vegetation was appreciated in most of the ecosystems where they were carried out the collections, that which possesses direct repercussion in the feeding and ovoposition of the mollusks. The municipality Santa Clara possesses a wide variety of species of mollusks, with medical marked importance, so much terrestrial as fluvial, that which develops the epidemic risk for entities that require of species of mollusks in her cycle of life; therefore, the identified taxons possesses the enough potentialities, as put up intermissions to parasites that affect, so much to the human health as to that of the rest of the animals.
