Analysis was conducted for the concentration of Chromium (Cr) and Nickel (Ni) in the river Ganga on four sampling sites at Prayagraj Uttar Pradesh and the bioaccumulation of these heavy metals in the crops grown in the area. The main aim of this analysis was to analyze the concentration of these heavy metals and study their bioaccumulation and biodistribution in the crops and assess their effects on human and aquatic life. The concentrations of these heavy metals were compared with WHO 1993. The concentrations were found to be above the maximum permissible limits, showing detrimental effect of their presence on crops grown near the sampling sites.