Current issues and concepts of multiple sclerosis

Multiple sclerosis is an autoimmune inflammatory demyelinating disease of the CNS. It is a progressive, immune-mediated disorder. Multiple sclerosis interrupts essential communication between brain and body.MS can damage your eyes but rarely permanent. The protective coverings of nerve cells are damaged, which leads to diminished function in the brain and spinal cord. MS is a disease with unpredictable symptoms that can vary in intensity. While some people experience fatigue and numbness, severe cases of MS can cause paralysis, vision loss, and diminished brain function. (1). The resulting inflammatory cascade releases cytokines and initiates destruction of the oligodendrocyte-myelin unit by macrophages. The axonal loss is the cause of the phase of the disease in which there is a progressive and persistent disability. (2) There is no cure to multiple sclerosis. Treatments attempts to improve function after an attack and prevents new attacks. Introduction of new drugs in last years building experience with their use.