Comparative study of inhaled salbultamol and ipratropium bromide in bronchial asthma

Objective: (i) To study pulmonary function test abnormalities in patients suffering from bronchial asthma. (ii) To assess the reversibility of bronco-constriction after inhalation of salbutamol & iptratropium bromide in these patients. (iii) To study comparative response of reversibility bronco constriction with salbutamol and ipratropium bromide in these patients. Materials and methods: The present study was undertaken in dept. of chest medicine GMC Nanded during period between 1/10/2001 to 15/1/2004 total 100 patients of bronchial asthma those who attended chest OPD were evaluated for efficiency of salbutamol & ipratropium. In selected 100 patients of bronchial spirometry done with computerized med graphics Spiro meter. Results: This study showed both salbutamol and ipratropium are effective bronchodilators in asthma patients. Although statistically over all response to salbutamol, appears to be superior. Conclusions: Overall improvement in lung functions with salbutamol was better as comparative ipratropium bromide.