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Assessment of renal function tests in Sudanese patients with recurrent typhoid fever in Gazera state – Sudan

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Author: 
Mutaz Ibrahim Hassan, Mohammed El-Siddiq Abbass, Asma AlaEldeen Abdo and Marwa Siddig Mohammed
Abstract: 

Background: Typhoid fever is caused by Salmonella typhi bacteria. Typhoid fever is rare in industrialized countries. However, it remains a serious health threat in the developing world, especially for children. Typhoid fever spreads through contaminated food and water or through close contact with someone who's infected. Signs and symptoms usually include high fever, headache, abdominal pain, and either constipation or diarrhea. Most people with typhoid fever feel better within a few days of starting antibiotic treatment, although a small number of them may die of complications. Vaccines against typhoid fever are available, but they're only partially effective.
Objectives: The aim of this study was to assess the renal function tests in Sudanese patients with typhoid in Gazera state- Sudan.
Results: The results of the study revealed significant variation between case and control group in the plasma level of Urea, Creatinine, Sodium and potassium. (P.Value ≤ 0.05). There was a significant decreased in Glomerular filtration rate in case group (108 ml/minute) compared to normal subjects.
Conclusions: There were obvious effects on RFT in all biochemical parameters used to evaluate the renal function.

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